Search results for "cluster [track data analysis]"
showing 10 items of 1171 documents
A low complexity distributed cluster based algorithm for spatial prediction
2017
Los mapas del entorno radioeléctrico (REM) pueden ser una herramienta esencial para numerosas aplicaciones en las futuras redes inalámbricas 5G. En este trabajo, empleamos un popular método geoestadístico llamado kriging ordinario para estimar el REM de un área cubierta por un eNodeB equipado con múltiples antenas. Los sensores inalámbricos se distribuyen por el área de interés y se organizan clústeres adaptativos de sensores para mejorar la calidad de la estimación del canal. En este trabajo, modificamos el algoritmo de clustering distribuido propuesto en un trabajo anterior para reducir la complejidad de la predicción de kriging. Se realizan simulaciones para detallar la técnica de formac…
An Immunogenic Peptide Derived from NM23-H2 Is Expressed on Bcr/abl+ Cells.
2006
Abstract Objective: Most tumors express antigens which, when presented by MHC molecules, can be recognized by cytotoxic T-lymphocytes. These tumor-associated-antigens (TAA) are considered to be key determinants in the graft-versus-tumor effect after allogeneic hematopoietic cell transplantation (HCT) and are therefore potential candidates for tumor vaccination. Unfortunately only small numbers of TAA have been isolated to date. In this project we looked for immunogenic peptides presented by bcr/abl+ cells of an HLA-A32 CML patient. Methods: Leukemia-specific mixed lymphocyte leukemia cell cultures (MLLC) were generated by co-culturing irradiated bcr/abl+ cells from the patient with peripher…
Identification of a Novel Pathway in BCR/ABL Signal Transduction Involving Akt-Independent Activation of PLC-gamma/mTOR/p70-S6K.
2006
Abstract In BCR/ABL positive CML, defining new, additional therapeutic targets in the pathways, activated by BCR/ABL is critical for the development of new treatment strategies, especially for patients resistant or refractory to Imatinib. While studying the involvement of PI3K/Akt/mTOR signaling pathway in the development of such resistance we have uncovered the existence of additional, Akt-independent mechanism of activation of mTOR/p70-S6 Kinase pathway. Short term treatment with Imatinib (1μM, 4 hours) of the BCR/ABL-positive cell lines LAMA84, AR320, KCL22, K562, Ba/F3-BCR/ABL caused downregulation of p70-S6K phosphorylation and of S6 ribosomal protein phosphorylation without decreasing…
Erwinia piriflorinigrans sp. nov., a novel pathogen that causes necrosis of pear blossoms
2010
Eight Erwinia strains, isolated from necrotic pear blossoms in València, Spain, were compared with reference strains of Erwinia amylovora and Erwinia pyrifoliae, both of which are pathogenic to species of pear tree, and to other species of the family Enterobacteriaceae using a polyphasic approach. Phenotypic analyses clustered the novel isolates into one phenon, distinct from other species of the genus Erwinia, showing that the novel isolates constituted a homogeneous phenotypic group. Rep-PCR profiles, PCR products obtained with different pairs of primers and plasmid contents determined by restriction analysis showed differences between the novel strains and reference strains of E. amylovo…
The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: pharmacogenomic determination of genes associated with sensitivity or resistance.
2013
(-)-Sesamin is a lignan present in sesam oil and a number of medicinal plants. It exerts various pharmacological effects, such as prevention of hyperlipidemia, hypertension, and carcinogenesis. Moreover, (-)-sesamin has chemopreventive and anticancer activity in vitro and in vivo. Multidrug resistance (MDR) of tumors leads to fatal treatment outcome in many patients and novel drugs able to kill multidrug-resistant cells are urgently needed. P-glycoprotein (MDR1/ABCB1) is the best known ATP-binding cassette (ABC) drug transporter mediating MDR. ABCB5 is a close relative to ABCB1, which also mediates MDR. We found that the mRNA expressions of ABCB1 and ABCB5 were not related to the 50% inhibi…
Asymptotic potentials and rate constants in the adiabatic capture centrifugal sudden approximation for X + OH(X-2 Pi) -> OX + H(S-2) reactions where …
2012
International audience; New long-range multipolar coefficients for the X + OH(X-2 Pi) interactions, where X = O(P-3), S(P-3) and N(S-4), are given here. They have been evaluated on the basis or monomer properties of the atoms and OH such as the dipole and quadrupole moments, and the static and dynamic polarizabilities. Each matrix element of the 18 x 18 (8 x 8 for N + OH) quasi-degenerate asymptotic potentials has been built up by means of the perturbation theory up to second order including or not the fine-structure of O, S and OH. The adiabatic potentials, obtained after diagonalization of the full matrix, show many crossings and complex behaviors near the asymptotes. Using the entrance c…
Evaluating the Effectiveness of Modelling-Oriented Workshops for Engineering Undergraduates in the Field of Thermally Activated Phenomena
2017
Two 20-h modelling-based workshops focused on the explanation of ther- mally activated phenomena were held at the University of Palermo, Italy, during the Academic Year 2014–2015. One of them was conducted by applying an inquiry-based approach, while the other, still based on laboratory and modelling activities, was not focused on inquiry. Seventy-two students belonging to the Undergraduate Program for Chemical Engineering attended the two workshops. The related content was focused on an à la Feynman unifying approach to thermally activated phenomena. Question- naires were administered to the students of both groups, before and post instruction. Responses were analysed using k-means cluster…
Molecular epidemiology of Acinetobacter baumannii in Iran: endemic and epidemic spread of multiresistant isolates
2014
Objectives We examined the molecular epidemiology of Acinetobacter baumannii clinical isolates from two cities (Tehran and Tabriz) of Iran. Methods DiversiLab repetitive extragenic palindromic PCR (rep-PCR), multilocus sequence typing and sequence group multiplex PCR were performed. The presence of resistance mechanisms including metallo-β-lactamases, extended-spectrum β-lactamases, OXA carbapenemases, aminoglycoside-modifying enzymes and RNA methylases was also investigated. Results DiversiLab rep-PCR identified 11 clusters and 11 singleton isolates. Twelve sequence types (STs), including six novel types, were identified. Sequence groups (SGs) 1-3 as well as five additional banding pattern…
Archetypal analysis: an alternative to clustering for unsupervised texture segmentation
2019
Texture segmentation is one of the main tasks in image applications, specifically in remote sensing, where the objective is to segment high-resolution images of natural landscapes into different cover types. Often the focus is on the selection of discriminant textural features, and although these are really fundamental, there is another part of the process that is also influential, partitioning different homogeneous textures into groups. A methodology based on archetype analysis (AA) of the local textural measurements is proposed. AA seeks the purest textures in the image and it can find the borders between pure textures, as those regions composed of mixtures of several archetypes. The prop…
Remote sensing image segmentation by active queries
2012
Active learning deals with developing methods that select examples that may express data characteristics in a compact way. For remote sensing image segmentation, the selected samples are the most informative pixels in the image so that classifiers trained with reduced active datasets become faster and more robust. Strategies for intelligent sampling have been proposed with model-based heuristics aiming at the search of the most informative pixels to optimize model's performance. Unlike standard methods that concentrate on model optimization, here we propose a method inspired in the cluster assumption that holds in most of the remote sensing data. Starting from a complete hierarchical descri…